sturza-adrian

Biography

Name:

Adrian Sturza

Title:

Associate Professor

Institution:

”Victor Babes” University of Medicine and Pharmacy - Department of Functional Sciences-Pathophysiology, Timisoara, Romania

Email:

[email protected]

Website:

www.umft.ro

Early career investigator (ECI):

No

Short biography of member:

WORK EXPERIENCE: 2016 → present - Associate Professor, 2014 → 2016 – Lecturer, 2013 → 2014 - Assistant Professor, Pathophysiology Department ”Victor Babes” University of Medicine and Pharmacy, Timisoara (Romania); 2016 → present - MD, Specialist in Diabetes, nutrition and metabolic disorders, Center of Diabetes, Nutrition and Disorders of Metabolism, Timișoara County Hospital, Romania; 2011 → 2016 - MD, Diabetes, nutrition and metabolic disorders (residency), Clinic of Diabetes, Nutrition and Disorders of Metabolism, Timisoara County Hospital, Romania; 2010 - MD, Laboratory medicine (residency), Timișoara County Hospital, Romania. EDUCATION AND TRAINING: 2009 → 2013 - PhD student / PhD in Medicine with Summa cum laudae distinction, Department of Pathophysiology “Victor Babes” University of Medicine and Pharmacy, Timisoara (Romania) and Institute for Cardiovascular Physiology, Goethe University, Frankfurt am Main (Germany) (co-tutorship, Prof Dr. Danina M. Muntean and Prof. Dr. Ralf Brandes); 2003 → 2009 - Medical student / Medical Doctor (MD), ”Victor Babes” University of Medicine and Pharmacy, Timisoara (Romania). SCIENTIFIC ACTIVITY: Member of Center for Translational Research and Systems Medicine of the “Victor Babes” University of Medicine and Pharmacy, Timisoara (Romania), https://erris.gov.ro/Center-for-Translational-Res ; Member in 5 International Projects; Director of 2 National Project (institutional competition); Responsible of 1 National Project (institutional competition for partnerships in basic research); Member in 2 National Projects; PRIZES - a total number of 24 in international and national meetings; H index=6 (Scopus), 5 (Web of Science)

Country:

RO, Romania

Publications list:

Monoamine oxidases are mediators of endothelial dysfunction in the mouse aorta. Sturza A, Leisegang MS, Babelova A, Schröder K, Benkhoff S, Loot AE, Fleming I, Schulz R, Muntean DM, Brandes RP. Hypertension. 2013 Jul;62(1):140-6. doi: 10.1161/HYPERTENSIONAHA.113.01314. Epub 2013 May 13. PMID: 23670301, https://www.ncbi.nlm.nih.gov/pubmed/23670301

Leptin potentiates endothelium-dependent relaxation by inducing endothelial expression of neuronal NO synthase. Benkhoff S, Loot AE, Pierson I, Sturza A, Kohlstedt K, Fleming I, Shimokawa H, Grisk O, Brandes RP, Schröder K. Arterioscler Thromb Vasc Biol. 2012 Jul;32(7):1605-12. doi: 10.1161/ATVBAHA.112.251140. Epub 2012 May 10. PMID: 22580898, https://www.ncbi.nlm.nih.gov/pubmed/22580898

Monoamine oxidase-A inhibition reverses endothelial dysfunction in hypertensive rat aortic rings. Sturza A, Mirică SN, Duicu O, Gheorgheosu D, Noveanu L, Fira-Mlădinescu O, Muntean DM. Rev Med Chir Soc Med Nat Iasi. 2013 Jan-Mar;117(1):165-71. PMID: 24505910, https://www.ncbi.nlm.nih.gov/pubmed/24505910

Monoamine oxidases are novel sources of cardiovascular oxidative stress in experimental diabetes. Sturza A, Duicu OM, Vaduva A, Dănilă MD, Noveanu L, Varró A, Muntean DM. Can J Physiol Pharmacol. 2015 Jul;93(7):555-61. doi: 10.1139/cjpp-2014-0544. Epub 2015 Mar 12. PMID: 25996256, https://www.ncbi.nlm.nih.gov/pubmed/25996256

Monoamine Oxidases as Potential Contributors to Oxidative Stress in Diabetes: Time for a Study in Patients Undergoing Heart Surgery. Duicu OM, Lighezan R, Sturza A, Ceausu RA, Borza C, Vaduva A, Noveanu L, Gaspar M, Ionac A, Feier H, Muntean DM, Mornos C. Biomed Res Int. 2015;2015:515437. doi: 10.1155/2015/515437. Epub 2015 May 25. Review. PMID: 26101773, https://www.ncbi.nlm.nih.gov/pubmed/26101773

Acute inhibition of monoamine oxidase and ischemic preconditioning in isolated rat hearts: interference with postischemic functional recovery but no effect on infarct size reduction. Dănilă MD, Privistirescu AI, Mirica SN, Sturza A, Ordodi V, Noveanu L, Duicu OM, Muntean DM. Can J Physiol Pharmacol. 2015 Sep;93(9):819-25. doi: 10.1139/cjpp-2015-0103. Epub 2015 Jun 30. PMID: 26322912, https://www.ncbi.nlm.nih.gov/pubmed/26322912

Modulation of mitochondrial respiratory function and ROS production by novel benzopyran analogues. Petruş A, Duicu OM, Sturza A, Noveanu L, Kiss L, Dănilă M, Baczkó I, Muntean DM, Jost N. Can J Physiol Pharmacol. 2015 Sep;93(9):811-8. doi: 10.1139/cjpp-2015-0041. Epub 2015 Jun 30. PMID: 26325241, https://www.ncbi.nlm.nih.gov/pubmed/26325241

Assessment of Mitochondrial Dysfunction and Monoamine Oxidase Contribution to Oxidative Stress in Human Diabetic Hearts. Duicu OM, Lighezan R, Sturza A, Balica R, Vaduva A, Feier H, Gaspar M, Ionac A, Noveanu L, Borza C, Muntean DM, Mornos C. Oxid Med Cell Longev. 2016;2016:8470394. doi: 10.1155/2016/8470394. Epub 2016 Apr 13. PMID: 27190576, https://www.ncbi.nlm.nih.gov/pubmed/27190576

The Role of Mitochondrial Reactive Oxygen Species in Cardiovascular Injury and Protective Strategies. Muntean DM, Sturza A, Dănilă MD, Borza C, Duicu OM, Mornoș C. Oxid Med Cell Longev. 2016;2016:8254942. doi: 10.1155/2016/8254942. Epub 2016 Apr 21. Review. PMID: 27200148, https://www.ncbi.nlm.nih.gov/pubmed/27200148

Monoamine oxidase inhibition improves vascular function in mammary arteries from nondiabetic and diabetic patients with coronary heart disease. Lighezan R, Sturza A, Duicu OM, Ceausu RA, Vaduva A, Gaspar M, Feier H, Vaida M, Ivan V, Lighezan D, Muntean DM, Mornos C. Can J Physiol Pharmacol. 2016 Oct;94(10):1040-1047. Epub 2016 Mar 22. PMID: 27322151, https://www.ncbi.nlm.nih.gov/pubmed/27322151

The effect of purinergic signaling via the P2Y11 receptor on vascular function in a rat model of acute inflammation. Dănilă MD, Privistirescu A, Duicu OM, Rațiu CD, Angoulvant D, Muntean DM, Sturza A. Mol Cell Biochem. 2017 Jul;431(1-2):37-44. doi: 10.1007/s11010-017-2973-5. Epub 2017 Feb 17. PMID: 28213772, https://www.ncbi.nlm.nih.gov/pubmed/28213772

Methylene blue improves mitochondrial respiration and decreases oxidative stress in a substrate-dependent manner in diabetic rat hearts. Duicu OM, Privistirescu A, Wolf A, Petruş A, Dănilă MD, Raţiu CD, Muntean DM, Sturza A. Can J Physiol Pharmacol. 2017 Nov;95(11):1376-1382. doi: 10.1139/cjpp-2017-0074. Epub 2017 Jul 24. PMID: 28738167, https://www.ncbi.nlm.nih.gov/pubmed/28738167

Contribution of monoamine oxidases to vascular oxidative stress in patients with end-stage renal disease requiring hemodialysis. Uțu D, Pantea S, Duicu OM, Muntean DM, Sturza A. Can J Physiol Pharmacol. 2017 Nov;95(11):1383-1388. doi: 10.1139/cjpp-2017-0067. Epub 2017 Jul 28. PMID: 28753408, https://www.ncbi.nlm.nih.gov/pubmed/28753408

Quercetin exerts an inhibitory effect on cellular bioenergetics of the B164A5 murine melanoma cell line. Sturza A, Pavel I, Ancușa S, Danciu C, Dehelean C, Duicu O, Muntean D. Mol Cell Biochem. 2018 Jan 29. doi: 10.1007/s11010-018-3296-x. [Epub ahead of print] PMID: 29380243, https://www.ncbi.nlm.nih.gov/pubmed/29380243