przemyslaw-leszek

Biography

Name:

Przemysław Leszek

Title:

MD, PhD

Institution:

Institute of Cardiology, Warszawa, Poland

Email:

[email protected]

Website:

www.ikard.pl

Early career investigator (ECI):

No

Short biography of member:

Fully clinically active cardiologist dealing in daily diagnostics, treatment of patients with heart failure (acute, chronic), and eligibility for cardiac transplantation and long-term left ventricular support. Parallel conducting research mainly covering the subject: Heart Failure, remodelling process, molecular biology and genetics (Iron homeostasis, Natriuretic Peptides, Heart rhythm and arrhythmia, telomeres physiology and several others aspects) and Cardio – oncology (Cardiotoxicity in oncology therapy, neuroendocrine tumors and relationship with heart diseases).

Country:

PL, Poland

Publications list:

1. Zhang, L.; Salgado-Somoza, A.; Vausort, M.; Leszek, P.; Devaux, Y. Regulation of the balance between cardiac and skeletal muscle triadin by a heart-enriched antisense long non-coding RNA; EUROPEAN JOURNAL OF HEART FAILURE 2017; 19; 1: 600 2. Sobieszczańska-Małek M, Korewicki J, Komuda K, Karczmarz M, Szymańska S, Cicha-Mikołajczyk A, Bekta P, Parulski A, Pronicki M, Grajkowska W, Małek G, Leszek P, Kaczorowska M, Kuśmierczyk M, Zieliński T. Heart Transplantation and Risk of Cardiac Vasculopathy Development: What Factors Are Important? Ann Transplant. 2017 Nov 17;22:682-688. 3. Zhang L, Salgado-Somoza A, Vausort M, Leszek P, Devaux Y; Cardiolinc™ network.: A heart-enriched antisense long non-coding RNA regulates the balance between cardiac and skeletal muscle triadin. Biochim Biophys Acta. 2017 Nov 8;1865(2):247-258. 4. Rajtik T, Goncalvesova E, Varga ZV, Leszek P, Kusmierczyk M, Hulman M, Kyselovic J, Ferdinandy P, Adameova A. Posttranslational modifications of calcium/calmodulin-dependent protein kinase IIδ and its downstream signaling in human failing hearts. Am J Transl Res. 2017 Aug 15;9(8):3573-3585. 5. Szobi A, Gonçalvesová E, Varga ZV, Leszek P, Kuśmierczyk M, Hulman M, Kyselovič J, Ferdinandy P, Adameová A. Analysis of necroptotic proteins in failing human hearts. J Transl Med. 2017 Apr 28;15(1):86. doi: 10.1186/s12967-017-1189-5. 6. Straburzyńska-Migaj E, Nessler J, Gruchała M, Kamiński K, Lelonek M, Leszek P, Mizia-Stec K, Rozentryt P, Gackowski A, Gwizdała A, Jankowska EA, Ponikowski P. Sacubitril/valsartan for treatment of chronic heart failure with reduced ejection fraction. Can all patients benefit? A position statement paper of experts of the Heart Failure Working Group of the Polish Cardiac Society. Kardiol Pol. 2017;75(3):286-293. doi: 10.5603/KP.2017.0056 7. Leszek, P.; Paterek, A.; Kepska, M.; Kolodziejczyk, J.; Mackiewicz, U.; Maczewski, M.; Heart rate reduction brings immediate beneficial hemodynamic effects in heart failure; EUROPEAN HEART JOURNAL 2016; 37: 435-436 8. Vausort, Melanie; Salgado-Somoza, Antonio; Zhang, Lu; Leszek, Przemyslaw; Scholz, Markus; Teren, Andrej; Burkhardt, Ralph; Thiery, Joachim; Wagner, Daniel R.; Devaux, Yvan; Myocardial Infarction-Associated Circular RNA Predicting Left Ventricular Dysfunction; JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 2016; 68;11: 1247-1248 9. Rywik TM, Janas J, Klisiewicz A, Leszek P, Sobieszczańska-Małek M, Kurjata P, Rozentryt P, Korewicki J, Jerzak-Wodzyńska G, Zieliński T. Prognostic value of novel biomarkers compared with detailed biochemical evaluation in patients with heart failure. Pol Arch Med Wewn. 2015;125(6):434-42. 10. Baán JA, Varga ZV, Leszek P, Kuśmierczyk M, Baranyai T, Dux L, Ferdinandy P, Braun T, Mendler L Myostatin and IGF-I signaling in end-stage human heart failure: a qRT-PCR study. J Transl Med. 2015 Jan 16;13:1. doi: 10.1186/s12967-014-0365-0. 11. Leszek, Przemyslaw; Sochanowicz, Barbara; Brzoska, Kamil; Danko, Bozena; Kraj, Leszek; Kusmierczyk, Mariusz;Piotrowski, Walerian; Sobieszczanska-Malek, Malgorzata; Rywik, Tomasz M.; Polkowska-Motrenko, Halina; Kruszewski, Marcin; Does myocardial iron load determine the severity of heart insufficiency? INTERNATIONAL JOURNAL OF CARDIOLOGY 2015; 182: 191-193 12. Leszek, Przemyslaw; Sochanowicz, Barbara; Szperl, Malgorzata; Kolsut, Piotr; Brzoska, Kamil; Piotrowski, Walerian; Rywik, Tomasz M.; Danko, Bozena; Polkowska-Motrenko, Halina; Rozanski, Jacek M.; Kruszewski, Marcin; Myocardial iron homeostasis in advanced chronic heart failure patients; INTERNATIONAL JOURNAL OF CARDIOLOGY 2012; 159; 1: 47-52