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Carlo Gabriele Tocchetti
Associate Professor of Medicine
Federico II University, Naples, Italy
Early career investigator (ECI):
Short biography of member:
Prof. Carlo Gabriele Tocchetti got his MD in 1997, his Board in Cardiology in 2001 and his PhD in 2007 at Federico II University, Naples, Italy, and is currently Associate Professor of Medicine in the Department of Translational Medical Sciences, Federico II University, Naples, Italy since 2014. He coordinates the Heart Failure outpatient unit mostly dedicated to post ischemic HF, RV dysfunction and Pulmonary Hypertension, and in particular to the follow-up of oncologic patient before, during and after undergoing antineoplastic protocols, and has established himself as a HF basic and clinical investigator. Prof. Tocchetti is Fellow of the Heart Failure Association (HFA), member of the Study Group on Cardio-Oncology of the HFA and of the WG on Myocardial Function of the European Society of Cardiology (ESC), and previous member of the Translational Research Committee of the HFA. His previous studies and ongoing collaborations with Drs Kass and Paolocci at Johns Hopkins University, Baltimore, MD, USA, have helped dissecting the cardiac contractile effects of HNO and the development of a novel HNO donor for treating human heart failure currently used in clinical trials. Hence, the main goal of his lab is to explore pathophysiologic mechanisms and therapeutic targets in cardiac dysfunction, with a particular interest on post-ischemic HF, genetic and inflammatory cardiomyopathies, Pulmonary Hypertension and RV dysfunction, and HF due to antineoplastic therapies, including novel anticancer immunotherapies and biologic drugs employed in inflammatory diseases.